What are best supplements? are there any that i should definitely take

I can see that DR Hain suggests Magnesium, Riboflavin, Co Q10 and Butterbur

That’s really wierd. Ive seen posts here in the past from other patients to whom both efexor and topamax have been prescribed at once like MAVPRINCESS. I myself am on an snri cymbalta and topamax. I wonder why Dr Hain is against mixing efexor with topamax?