Why do the drugs suddenly stop working?

It rather looks as if Lyrica has stopped working. This bloody disease. After trying many many drugs I thought I had found something that worked.Apart from the odd blip if I did too much , pregabalin worked for 6 months opening up my life after 3 years of being house bound locked in one bloody room. The fact is after this game of cat and mouse I can’t go back to not going out and meeting people…I simply can’t…sorry to rant but this disease has robbed me of my job, savings and dignity…and I’m so tired of it.

Yes, I think many of us have had a repreive, only to be socked in the stomach by a medicine not working. I tried Remeron in the very beginning of this and I was “cured” within a month. I was so happy not to have the 24/7 anxiety, insomnia, dizziness, visual b.s. and I had already booked a trip to see Dr. Hain. I was going to cancel it since I was doing swimmingly on the Remeron…and then it stopped. I tried to go up on it…couldn’t…I was so sad and scared. But what is a good thing is that I realized it was a chemical issue for me after so many tests came back “normal”…it was messed up chemistry. Eventually I went on and got my cocktail, and yes I worry that it will poop out too. But there are other meds to try, and I will have to hit it at another angle if that happens. I don’t ever want to go back there…that was the darkest place I’ve ever been in my life. I know you understand.
SO pull your boots on and get to figuring out a different med that might work. You can’t let MAV win…

Fiona, I completely know what you’re going through as the same thing appears to have happened to me. I’ve been on Lyrica for about six months and recently crashed and although a bit better I’m shocked and devastated this effing thing has broken through. I’m on 400mg and am seeing Dr S on Wednesday to demand some answers and maybe add another med. I’ll let you know how I fare.

Meanwhile we can only take one day at a time, but try and keep positive.