100 meds for migraine, dont give up

hi every one ,for those of you who may have migraine or suspect mav.
if one med dosnt work look at this list.
from jen cheers

Headache and Migraine Preventives:
It’s Impossible to Have Tried Everything!
When discussing preventive medications, it’s not at all unusual to
hear someone with frequent Migraines or headaches say, “I’ve tried
everything!” In the reality of today’s headache and Migraine
medicine, that’s just not possible. As you can see from the list
below, there are over 100 medications and dietary supplements, as
well as at least one medical device, being used successfully for
headache and Migraine prevention. There are also virtually endless
combinations of them. Many people find that it’s not a single
medication or supplement that ends up being successful for them, but
a combination of preventives.
The following medications are being used successfully by some
headache and Migraine patients as preventive medications. They’re
listed first by their generic names, followed by some of their brand

ANTIHYPERTENSIVES (blood pressure meds)
Alpha-2 agonists:

Clonidine, aka Catapres
Guanfacine, aka Tenex
ACE Inhibitors:

Benazepril, aka Lotensin
Captopril, aka Capoten
Enalapril, aka Vasotec
Fosinopril, aka Monopril
Lisinopril, aka Zestril, Prinivil
Moexipril, aka Univasc
Perindopril, aka Aceon
Quinapril, aka Accupril
Ramipril, aka Altace
Trandolapril, aka Mavik

Alzheimer’s/Dementia Medicaton:

Memantine, aka Namenda

Angiotensin II Inhibitors:

Candesartan, aka Atacand
Eprosartan, aka Teveten
Irbesartan, aka Avapro
Losartan, aka Cozaar
Olmesartan, aka Benicar
Telmisartan, aka Midcardis
Valsartan, aka Diovan

Beta Blockers:

Acebutolol, aka Secral
Atenolol, aka Tenormin
Betaxolol, aka Kerlone
Bisoprolol, aka Zebeta, Emconcor
Cartelol, aka Cartrol
Labetalol, aka Normodyne, Trandate
Metoprolol, aka Lopressor
Nadolol, aka Corgard
Penbutololm aka Levatol
Pindolol, aka Visken, Syn-Pindolol
Propranolol, aka Inderal
Timolol, aka Blocadren

Calcium Channel Blockers:

Amlodipine, aka Norvasc
Bepridil, aka Vascor
Diltiazem, aka Cardizem, Tiazac
Felodipine, aka Plendil
Flunarizine, aka Sibelium (Canada)
Isradipine, aka DynaCirc
Nicardipine, aka Cardene
Nifedipine, aka Adalat, Procardia
Nimodipine, aka Nimotop
Nisoldipine, aka Sular
Verapamil, aka Calan, Verelan, Isoptin


Cyproheptadine, aka Periactin
Pizotifen, aka Sandomigran (UK)

Tricyclic antidepressants (TCAs):

Amitriptyline, aka Elavil (discontinued), Endep
Amoxapine, aka Asendin
Clomipramine, aka, Anafranil
Desipramine, aka Norpramin
Doxepin, aka Sinequan
Imipramine, aka Norfranil, Tofranil
Nortriptyline, aka Pamelor, Aventyl
Protriptyline, aka Vivactil
Trimipramine, aka Surmontil
MAOI Antidepressants:

Isocarboxazid, aka Marplan
Phenelzine, aka Nardil
Tranylcypromine, aka Parnate
Selective serotonin reuptake inhibitors (SSRIs):

Citalopram, aka Celexa
Escitalopram oxalate, aka Lexapro
Fluoxetine, aka Prozac
Fluvoxamine, aka Luvox
Paroxetine, aka Paxil
Sertraline, aka Zoloft
Selective serotonin and norepinephrine reuptake inhibitors (SSNRIs):

Duloxetine hydrochloride, aka Cymbalta
Venlafaxine, aka Effexor, Effexor XR
Other Antidepressants:

Bupropion, aka Wellbutrin, Zyban
Mirtazepine, aka Remeron
Trazodone, aka Desyrel

Attention Deficit Hyperactivity Disorder Meds:

Dextroamphetamine, aka Adderall
Atomoxetine HCl, aka Strattera
Methylphenidate HCl, aka Concerta, Ritalin
Pemoline, aka Cylert

Cox-2 Enzyme Inhibitors:

Celecoxib, aka Celebrex


Carisoprodol, aka Soma
Cyclobenzaprine, aka Flexeril
Lioresal, aka Baclofen
Metaxalone, aka Skelaxin
Tizanidine, aka Zanaflex

Many people call this class of medications “antiseizure
medications.” Actually, these meds are neuronal stabilizing agents.
They work to stabilize the neuronal activity in the brain.
Considering that Migraineurs have overactive neurons in the brain
that, when a trigger is encountered, start firing in a wave and
start a chain reaction that produces the symptoms of a Migraine
attack, it makes sense to use them for Migraine prevention. These
meds are only antiseizure meds when they’re being used to prevent
seizure activity.

Carbamazepine, aka Tegretol
Clonazepam, Klonopin
Clorazepate, aka Tranxene
Divalproex, aka Depakote
Gabapentin, aka Neurontin
Levetiracetam, Keppra
Lamotrigine, aka Lamictal
Oxcarbazepine, Trileptal
Tiagabine, aka Gabitril
Topiramate, aka Topamax
Valproate Sodium, aka Depacon
Zonisamide, aka Zonegran
Pregabalin, aka Lyrica


Methylergonovine, aka Methergine (the only ergot used as a


Montelukast, aka Singulair
Zafirlukast, aka Accolate
Zyleuton, aka Zyflo


Baclofen, aka Lioresal
Botulinum Toxin Type A, aka Botox
Memantine, aka Namenda


Coenzyme Q10
Butterbur, aka Petadolex
Vitamin B2
5-HTP (Check carefully with doctor because of interactions with meds
including triptans and SSRIs)


The NTI Tension Suppression System, invented by Dr. Jim Boyd, has
proven quite effective for some people who have problems with
clenching or grinding their teeth in their sleep.

This list will be updated as more medications are successfully used
for headache and Migraine prevention. If you’re having problems
finding an effective preventive regimen, sharing this list with your
doctor may be helpful to you.


Ramadan, Nahib M., MD; Silberstein, Stephen D., Md, FACP; Frietag,
Frederick G., DO; Gilbert, Thomas T., MD, MPH; Frishberg, Benjamin
M., MD. “Evidence-Based Guidelines for Migraine Headache in the
Primary Care Setting: Pharmacological Management for Prevention of
Migraine.” American Academy of Neurology Practice Guidelines.
September, 2000.

Good post, and absolutely true.

Thanks Jenny for the long list of meds. I’ve always wondered about how many meds can be used as preventatives.

I think that when a person says that they have tried them all, they may be refering to what their doctor believes is all. This list may be useful to take to doctors to discuss.

Youre welcome,thanks for the info on occular migraine i’ll go look it up.

Hi all,

Have just brought this post by jennyd to the front, I’m always referring to it and for anyone who might be new to this forum, they may find it really useful.

Actually, trolling through past posts is really informative, I’ve just commented about me starting a new SSRI antidepressant, Lexapro and I found a post which states that they apparently work as ‘opposites’ to my current med Sandomigran :cry: . So unfortunately I’ll have to drop this one and wait to see my neuro (he didn’t prescribe these by the way…I managed to get some prescribed elsewhere as I thought I knew better (lol)!!!)

Back to the drawing board, but NEVER give up hope!! :stuck_out_tongue:

regards Judy

Yes Rich, it’s called diamox.

headaches.about.com/od/medicatio … l_prof.htm


Do you know much about the medication used for Alziehmeres and now for Migraines called Namenda?? That might be a possibility in the future.


I knew the list was long, but that is a lot longer than I had imagined.

Hi Joe , No I don’t know much about it,
I know some of the mal dedebarquement group tried it ,
some had not bad results others had no benefit .
but I have heard neurologists and docs dont give it over easily.
sorry Joe.


Bumped up again because its so incredibly important.

I should have known it was our beloved Jen who posted this!!! Where are you Jen, HOW are you Jen??? We all miss you!


Thanks for that Kim, i was actually looking for this list :wink:

Such a shame that most of them have weight gain as a side effect…amongst other things. Not much good for anybody currently undergoing therapy for body image/weight related issues. Rock and a hard place really. My GP insisted that amitriptyline at small doses does not cause weight gain. Research on the web would suggest this is very wrong: amitriptyline and most of the tri-cyclics have very high profile for weight gain. Topiramate doesn’t. But that gave me suicidal thoughts and severe depression after 3 weeks. And the dry mouth and nausea from lamotrigine is hideous. Would be good to hear how people have reacted to different meds as everybody is different.

Topamax is making my hair fall out!

I’ve gained weight on propanolol. I’ll still take it over the way I was feeling before I started it.


Yea, i could actually use some weight. Topamax has also stolen my appetite. I have to eat on a schedule. And I was a light weight to begin with.

Why don’t they tell you these things?

All Hain said was to expect a little tingling and maybe some memory problems.

I’ll bet a lot of people here would disagree with that!

No mention of hair loss. No mention of loss of appetite. No mention of having to get my creatinine and HCO3 checked yearly. No mention of drinking lots of water if i have a family history of kidney stones. Although, to his credit, he does ask about some of these symptoms at follow-up visits. So maybe he doesn’t talk about them upfront is so as not to put them in your head.

Dang these meds, but what would we do without them.


When I first started Topamax I was shaving my head every other day, of course I wasn’t worried about hair fallout :wink:

Lets keep trying to work togather and stop this spinnging.



You are a team player! And you have given me a new sense of hope :!:

Thanks for your hair story. Maybe if I start shaving mine every other day it will come back thicker !!!

Hey, since we’re a team now, can I have some of yours? :mrgreen:


Darn the luck :oops:

But I’ll ask Sandra to put it in a bag next time :idea:


I just saw your picture - it will be a perfect match for mine! :mrgreen:

Things are looking up!