New to MAV and new to the site - first of all - thanks to the many of you who have already given me great feedback. I have learned that this disease is a mystery to both patient and doctor. Apparently - I have made good progress according to my doctor on Topamax. I have regressed with symptoms a couple of times - once when I got sick with the flu - and once when my meds were boosted. It seems tweaking my meds does seem to cause a problem. Since the onset of original sympoms - I went through about 4-5 months of a downward slide where they couldn’t find what was wrong with me. I am currently on the upswing and the meds are helping - For those of you who have had this for a while, how do you cope with working long hours? Have you had to change careers? I have had to leave my position which was very challenging mentally - will I be able to return at some point?