Some interesting points on Effexor from the below paper
In our study, venlafaxine can also decrease vertigo attack frequency and severity. We believe that venlafaxine confers some advantages over other medications for VM prophylaxis through several factors. Similar to the onset of migraine, 5-HT levels affect the onset of vestibular symptoms (24, 25). Venlafaxine decreases 5-HT levels and subsequently vertigo attack frequency and can also reduce the levels of certain inflammatory cytokines (26–28) that play a role in episodic vertigo. Venlafaxine also exerts neuroprotection effects (29) that may decrease the severity of vertigo.
In our preliminary study, where we found that a daily dose of 37.5 mg had similar effects to the maximum daily dose of 75 mg. Therefore, we used 37.5 mg as the maximum daily dose in this study to further reduce side effects.
I had earlier posted about the findings of inflammatory cytokines in blood test in all patients with Vestibular migraine. Venlaflaxine helps with that.