I have tried searching for this on the forum but can’t find much about it so thought I’d ask specifically.
My GP has recommended I come off Pizotifen as it isn’t doing anything to help my migraines (my head hurts around 70% of the time) and dizziness (every day). And when I tried increasing beyond 2mg I got more dizzy. And as I started taking it just after I’d had labyrinthitis (which took 2 months to really start to ease) we don’t know if it is actually triggering the dizziness as before that I didn’t have dizziness every day, but rather associated with my migraines.
Anyway, the next medication on the list from the Neurologist is Imipramine. Apparently this is an older tricyclic antidepressant and my GP has never actually prescribed it before. And when I tried searching online there wasn’t much information about its use for migraines. It seems amitriptyline is used more frequently. But my husband seems to remember me trying this years ago for something else (I honestly can’t remember ever taking it, but I have taken a lot through the years as I have multiple health issues) and apparently I couldn’t tolerate it. So I’m obviously a little bit nervous about trying it.
However I really need to try something. Even only taking painkillers on my worst days I had to take something 16 days last month and the neurologist said no more than 10. And twice in the past two months I’ve had intractable migraines that have gone on for days without relief even hitting them with sumatriptan, naproxen, and paracetamol as much as possible. And I’ve had to start taking Prochlorperazine again as the dizziness and vertigo has got so bad at times. Hence the conclusion the Pizotifen is doing nothing and I need to try something else.
I’m hoping it might help with my anxiety too, which has sky rocketed this year. But the anxiety also kicks in at the thought of weaning off Pizotifen and onto imipramine. I feel flu-like at the moment dropping down off the Pizotifen and am due to start imipramine on Tuesday. So wondered if anyone else had tried this and could share how they got on with it.