Need advise re flying please

Hi there
I have had Mav for a few years now,I take pizotifen and propranolol.
Anyway hubby’s family are absolutely desperate for us to go see them(I’m UK,they’re USA) so we’ve booked the flight
I have never ever flown so on top of the nerves of never having flown before I’m worried about it triggering Mav(also the 6 hour time zone difference)
Can anyone tell me what sensations I need to expect on the plane please and also any tips anyone has!
Thanks so much

Please use search, there are loads of existing topics on flying with MAV.