New CGRP approved on NHS

Medication 💊 CGRP antagonists
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Eptinezumab (also called Vyepti) is now available on NHS for those in the UK. It differs from other CGRP drugs in that its an IV infusion which is administered in a medical care setting, not as an at home injection. Its meant to last 3 months. As with the others it can only be prescribed by a specialist when at least 3 migraine preventatives have been trialled.

Do these work for VM does anyone know?

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CGRP drugs seem less effective for vestibular migraine according to Dr. Hain at Northwestern Uni in Chicago, USA. I’ve tried a few CGRPs that didn’t work for me too, but anything is always worth a shot

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Do they always need to be injected or is there another way of administering them?

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There are now 4 drugs (erenumab etc.) NICE approved for migraine. Do they work for migraine with vertigo? Does anyone have any experience of them?

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Have you taken a look through existing Posts in #medication:cgrp-antagonists ?

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there are both oral and injectable forms. I have tried Nurtec and Ubrevly which are both oral forms, but none of the injectables

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I have tried Nurtec, Ubrevley, both oral CGRP’s and I have tried Emgality as an injectable. Unfortunately for me none of them helped in fact the injection made me more dizzy for a few weeks and also gave me terrible lower back pain and insomnia. Everyone is different though so it could work for you!

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yeah this treatment progression is from Dr. Hain. he says in his experience, people with VM normally dont get a whole lot of relief from CGRP drugs, but its always worth a shot. They are allegedly very safe, and I personally didn’t really get any side effects from trying a few of them.

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Thanks for sharing the decision tree. I forgot how many meds I’ve been on the years, I sure do remember the side effects. I disagree with his last box, Botox or anti-CGRP (rarely works). I attribute the combo to me having a somewhat normal life. I can tell when both wear off at the same time. It’s not pretty & I dread when the calendars align.

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