New CGRP approved on NHS

Eptinezumab (also called Vyepti) is now available on NHS for those in the UK. It differs from other CGRP drugs in that its an IV infusion which is administered in a medical care setting, not as an at home injection. Its meant to last 3 months. As with the others it can only be prescribed by a specialist when at least 3 migraine preventatives have been trialled.

Do these work for VM does anyone know?


CGRP drugs seem less effective for vestibular migraine according to Dr. Hain at Northwestern Uni in Chicago, USA. I’ve tried a few CGRPs that didn’t work for me too, but anything is always worth a shot


Do they always need to be injected or is there another way of administering them?

There are now 4 drugs (erenumab etc.) NICE approved for migraine. Do they work for migraine with vertigo? Does anyone have any experience of them?

Have you taken a look through existing Posts in #medication:cgrp-antagonists ?

there are both oral and injectable forms. I have tried Nurtec and Ubrevly which are both oral forms, but none of the injectables

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I have tried Nurtec, Ubrevley, both oral CGRP’s and I have tried Emgality as an injectable. Unfortunately for me none of them helped in fact the injection made me more dizzy for a few weeks and also gave me terrible lower back pain and insomnia. Everyone is different though so it could work for you!


yeah this treatment progression is from Dr. Hain. he says in his experience, people with VM normally dont get a whole lot of relief from CGRP drugs, but its always worth a shot. They are allegedly very safe, and I personally didn’t really get any side effects from trying a few of them.


Thanks for sharing the decision tree. I forgot how many meds I’ve been on the years, I sure do remember the side effects. I disagree with his last box, Botox or anti-CGRP (rarely works). I attribute the combo to me having a somewhat normal life. I can tell when both wear off at the same time. It’s not pretty & I dread when the calendars align.

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