Here’s one that take that combo 7 years some time back so it obviously happens. However as you say Dr Hain praises a Propranolol and Effexor combo as do others I’ve seen elsewhere. @nin takes both. She wrote recently ‘Propranolol is my friend. Venlafaxine an acquaintance’. You can follow her experiences with them through her PD or just search her posts. @mav, Karen, is another I recall who no longer posts but had great success with that combo recently. Search her likewise.
you, me and quite a few other regulars on here I suspect. Personally I’ve kept detailed logs, diaries etc, etc all in the hope just one day somebody might find them useful for research but, long ago, gave up holding my breath in anticipation and besides these days I hear only data collected in real time can be considered valid. I’d have thought anything was better than nothing but apparently that’s not the case unfortunately.
If it’s any help I’ve taken Propranolol by the bucketload it seems for more than five years and despite that and MAV I am not depressed. I know it does make people prone to depression depressed. I think depression is much like any other illness if it sees an Achilles Heel it bites it! But then I believe more and more that predisposition and genetics must account for the development of most illnesses. People get depressed on Effexor.