‘‘Researchers at University of Colorado School of Medicine may have figured out what causes Meniere’s disease and how to attack it. According to Carol Foster, MD, from the department of otolaryngology and Robert Breeze, MD, a neurosurgeon, there is a strong association between Meniere’s disease and conditions involving temporary low blood flow in the brain such as migraine headaches.’’
James - I ran this past a highly esteemed friend of the forum. His thoughts were that it was a nicely laid out but not a new idea. The rationale for using Serc (betahistine), the most widely prescribed Meniere’s medicine worldwide, is to improve and stabilise inner ear blood flow. He suspects this is the background pitch for a pharmaceutical company interested in inner ear drug delivery, probably with a neuroprotectant candidate drug.
Well I never knew about the atmospheric pressure playing such a big part in menieres, nor that menieres attacks can be terminated by lowering atmospheric pressure in a chamber, I found that most interesting.
Can someone explain what the “local hypothermia” means as a way to stop an attack? Interesting that they use “steroids” as well, as my friend has not had one vertigo attack since putting herself on “low dose” hydrocortisone.
James - I ran this past a highly esteemed friend of the forum. His thoughts were that it was a nicely laid out but not a new idea. The rationale for using Serc (betahistine), the most widely prescribed Meniere’s medicine worldwide, is to improve and stabilise inner ear blood flow. He suspects this is the background pitch for a pharmaceutical company interested in inner ear drug delivery, probably with a neuroprotectant candidate drug.
S 8)
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It may not be a new idea but I am grateful that someone is taking a look at this in regards to migraine playing a role.Proper Meniere hypothesized that migraine was involved somehow.When I have done searches there is very little research that I can find where migraine and blood flow are looked at as a cause.
It is usually stated that one of the key differences between VM and MM is the hearing loss.I have never seen a study that showed how this conclusion was reached.I don’t think ent’s and neuros have much communication between them,I could be wrong but I wonder some time.So for me I think that it is good that she and a neurologist are looking at this together.
If they are doing this to trial a new drug yippee,Serc did squat for me,as I am probably more mav in my makeup.The slides look like a lecture that she gave her students.
On an added note for anyone here who has Menieres as well, they are starting a new drug trial here in Sweden where they are using the same drug that is used for Glaucoma,intratypanic injection–did I spell that right? This is phase 2, in phase one they told me they got good results with hearing getting better but didn’t do so much for the vertigo.